The clinical value of parenteral immunonutrition in surgical patients

Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The authors assessed parenteral nutrition (PN) in surgical patients. Three strategies were compared: (A) standard PN; (B) standard PN supplemented with intravenous glutamine (Dipeptiven; Fresenius-Kabi) at a dose of 2.0 mL/kg per day; and (C) standard PN supplemented with intravenous omega-3-unsaturated fatty acids (Omegaven; Fresenius-Kabi) at a dose of 1.0 mL/kg per day. PN was prepared as All-in-One admixtures comprising Aminoplasmal 10% and 15% (B Braun) or Aminomel (Baxter) amino acid solutions, fatty acid emulsions (Lipofundin MCT/LCT 10% and 20%; B Braun), and glucose (10, 20 and 40% solutions).